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Director: |
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F.G. Issa, MD, PhD
Associate Professor
Sydney, Australia |
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Publications:
- Chaufour, X., F. Issa, C. Sullivan, C. Mclachlan, G. Unger. A fully-automated environmental chamber for examination of long-term effects of intermittent hypoxia on medium-size animals. Jpn. J. Physiol. 49:207-211 (1999). [Abstract]
- Schachter, L.M., C.M. Salome, A.M. Roberts, F.G. Issa, C.E. Sullivan, A.J. Woolcock. Change in lung volume with change in posture from upright to supine is not related to changes in airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 157;A515 (1998).
- Schachter, L.M., T. Kirjavainen, F.G. Issa, C.E. Sullivan, A.J. Woolcock. Inspiratory resistance and its association with inspiratory symptoms in asthmatics during airway challenge. Am. J. Respir. Crit. Care Med. 157;A671 (1998).
- McNamara, F., F. G. Issa, C. E. Sullivan. Arousal pattern following central and obstructive breathing abnormalities in infants and children. J. Appl. Physiol. 81;2651-2657 (1996) [Abstract]
- Vazquez, J.C., Masuda, A., Hajduk, E., Iyer, A., Tanguay, S., Flemons, W., Whitelaw, W., Issa, F.G. and Remmers, J.E. Hospital and home digital monitoring of sleep disordered breathing using arterial oxygen saturation and snoring sound. Am. J. Respir. Crit. Care Med. 153;A870 (1996).
- Issa, F.G. and Mitchell, I. Nocturnal respiratory disturbances of infancy and subsequent breathing pattern during childhood. In: Sleep Breathing Disorders and Sudden Infant Death Syndrome. National Center of Neurology and Psychiatry, Ministry of Health & Welfare, Japan, pp 135-141 (1995).
- Issa, F.G. and Porostocky, S. Gustatory stimulation of the oropharynx fails to induce swallowing during sleep. Gastroenterology 107;879-892 (1994). [Abstract]
- Issa, F.G. and Porostocky, S. Control of ventilation during continuous swallowing. Am. J. Respir. Crit. Care Med. 150;1274-1278 (1994). [Abstract]
- Issa, F.G., Porostocky, S and Feroah, T. Effect of sleep and sighing on upper airway resistance in the mongrel dog. J. Appl. Physiol. 76:856-861 (1994). [Abstract]
- Isono, S., Feroah, T.R., Hadjuk, E.A., Morrison, D.L., Launois, S.H., Issa, F.G., Whitelaw, W.A. and Remmers, J.E. Anatomy of the pharyngeal airway in sleep apneics: separating anatomic factors from neuromuscular factors. Sleep 16:S80-84 (1994).
- Issa, F.G., Remmers, J.E. and Hadjuk, E. Detection of sleep-disordered breathing by computerized oximetry. Am. Rev. Respir. Dis. 149:A181(1994).
- Issa, F.G. and Porostocky, S. Effect of continuous swallowing on respiration. Respir. Physiol. 95:181-193 (1994). [Abstract]
- Issa, F.G. and S. Porostocky. Augmentation of genioglossus muscle activity during partial paralysis of the parasternal muscle. Am. Rev. Respir. Dis. 147:A948 (1993).
- Issa, F.G. and S. Porostocky. Control of ventilation during swallowing. Am. Rev. Respir. Dis. 147:A162 (1993).
- Issa, F.G. and S. Porostocky. Upper airway resistance during sighing in the awake and sleeping dog. Am. Rev. Respir. Dis. 147:A950 (1993).
- Rimmer, K.P., Golar, S.D. , Issa F.G. and Whitelaw, W.A. Response to inspiratory resistive loads in patients with amyotrophic lateral sclerosis. Am. Rev. Respir. Dis. 147:A960 (1993).
- Launois, S.H., Feroah, T.R., Campbell, W.N., Issa, F.G. , Morrison, D., Whitelaw, W.A. and J.E. Remmers. Site of pharyngeal narrowing predicts outcome of surgery for obstructive sleep apnea. Am. Rev. Respir. Dis. 147:182-189 (1993). [Abstract]
- Issa, F.G. and Bitner, S. Effect of route of breathing on the ventilatory and arousal responses to hypercapnia in awake and sleeping dogs. J. Physiol. (London) 465:615- 628 (1993). [Abstract]
- Issa, F.G. and Porostocky, S. Effect of sleep on changes in breathing pattern accompanying sigh breaths. Respir. Physiol. 93:175-187 (1993). [Abstract]
- Issa, F.G., Morrison, D., Hadjuk,E., Iyer, R., Feroah, T. and Remmers, J. Digital monitoring of sleep disordered breathing using snoring sound and arterial oxygen saturation. Am. Rev. Respir. Dis. 148:1023-1029 (1993). [Abstract]
- Issa, F.G. Effect of clonidine in obstructive sleep apnea. Am. Rev. Respir. Dis. 145:435-439 (1992). [Abstract]
- Issa, F.G. and J.E. Remmers. Identification of a subsurface area in the ventral medulla sensitive to local changes in PCO2. J. Appl. Physiol. 72:439-446 (1992). [Abstract]
- Issa, F.G. and S. Bitner. Restructuring of sleep and reversal of respiratory muscle hypotonia during REM sleep following bilateral phrenicotomy. Neurosci. Lett. 139:231-233 (1992). [Abstract]
- Issa, F.G., D. Morrison, E. Hajduk, A. Iyer, W. Whitelaw, T. Feroah, and J. Remmers. Digital monitoring of sleep apnea using SaO2 and snoring signals. Am. Rev. Respir. Dis. 145:A722 (1992).
- Launois, S.H., Isono, S., Morrison, D.L., Feroah, T.R., Issa, F.G., Whitelaw,W.A. and Remmers, J.E. Static mechanics of the hypotonic nasopharynx in patients with obstructive sleep apnea during sleep. Am. Rev. Respir. Dis. 145:A210 (1992).
- Issa, F.G. Effect of clonidine in obstructive sleep apnea. Am. Rev. Respir. Dis. 143:A589 (1991).
- Issa, F.G. The ventilatory response to hypercapnia: effect of sleep state and route of breathing. Am. Rev. Respir. Dis. 143:A797 (1991).
- Issa, F.G. The arousal response to hypercapnia: effect of sleep state and route of breathing. Am. Rev. Respir. Dis. 143:A797 (1991).
- Remmers, J.E., Issa, F.G., and Suratt, P.M. Sleep and respiration, J. Appl. Physiol. 68:1286-1289 (1990).
- Remmers, J.E. and Issa, F.G. Indications and rationale for treatment of sleep- disordered breathing in older people. In: The Treatment of Sleep Disorders of Older People. Bethesda, Maryland, pp 55-57 (1990).
- Bye, P.T.P, Ellis, E.R., Issa, F.G., Donnelly, P.M. and Sullivan, C.E. Respiratory failure and sleep in neuromuscular disease. Thorax 45:241-247 (1990).[Abstract]
- Issa, F.G., Suratt, P.M. and Remmers, J.E. (eds). Progress in Clinical and Biological Research: Sleep and Respiration, Wiley-Liss, Inc., New York, Volume 345 (1990).
- Issa, F.G. and Remmers J.E. Central chemoreceptive elements in the medullary ventral surface. Am. Rev. Respir. Dis. 141:379 (1990).
- Issa, F.G. and Bell, S. Determinants of CPAP in patients with sleep apnea. Am. Rev. Respir. Dis. 141:862 (1990).
- Issa, F.G. and Remmers, J.E. Pathophysiology and treatment of obstructive sleep apnea. Current Pulmonol. 10:327-352 (1989).
- Issa, F.G., Szeto, E., Lauff, D. and Sullivan, C.E. Genioglossus and breathing responses to airway occlusion in dogs: effect of sleep and route of occlusion. J. Appl. Physiol. 64:543-549 (1988). [Abstract]
- Issa, F.G. and Remmers, J.E. Localization of a medullary area sensitive to changes in CO2 in in-vitro brainstem-spinal cord preparation of newborn rats. Soc. Neurosci Abstr. 14:935 (1988).
- Issa, F.G., McNamara, S.G. and Sullivan, C.E. Arousal responses to airway occlusion in sleeping dogs: comparison of nasal and tracheal occlusions. J. Appl. Physiol. 62:1832-1836 (1987). [Abstract]
- Sullivan, C.E., Issa, F.G., Ellis, E., Bruderer, J., McCauley, V., Bye, P.T., Grunstein, R. and Costas, L.J. Treatment of cardio-respiratory disturbances during sleep. Interdiscipl. Topics Gerontol. 22:47-67 (1987).
- Weil, J.V., Cherniack, N.S., Dempsey, J.A., et al. National Heart, Lung and Blood Institute, National Institute of Health Workshop: Respiratory Disorders of Sleep. Pathophysiology, clinical implications, and therapeutic approaches. Am. Rev. Respir. Dis. 136:755-761 (1987).
- Issa, F.G., Grunstein, R., Bruderer, J., Costas, L., McCauley, V., Berthon-Jones, M. and Sullivan, C.E. Five years experience with home nasal continuous positive airway pressure therapy for the obstructive sleep apnea syndrome. In: Sleep Related Disorders and Internal Diseases. J.H. Peter, T. Podszus and P. von Wichert (eds.), Springer-Verlag, Heidelberg, pp 360-365 (1987).
- Issa, F.G. and Sullivan, C.E. The immediate effects of nasal continuous positive airway pressure treatment on sleep pattern in patients with the obstructive sleep apnea syndrome. Electroencephalogr. Clin Neurophysiol. 63:10-17 (1986). [Abstract]
- Issa, F.G. and Sullivan, C.E. Reversal of central sleep apnea using nasal CPAP. Chest 90:165-171 (1986). [Abstract]
- McNamara, S.G., Issa, F.G., Szeto, E. and Sullivan, C.E. Influence of negative pressure applied to the upper airway on the breathing pattern in unanesthetized awake dogs. Respir. Physiol. 65:315-329 (1986). [Abstract]
- Goh, A.S.F., Issa, F.G. and Sullivan, C.E. Upper airway dilating forces during wakefulness and sleep in dogs. J. Appl. Physiol. 61:2148-2155 (1986). [Abstract]
- Sullivan, C.E. and Issa, F.G. Obstructive sleep apnea. Clin. Chest Med. 6:633-650 (1985). [Abstract]
- Issa, F.G. and Sullivan, C.E. Respiratory muscle activity and thoraco-abdominal motion during acute episodes of asthma in sleep. Am. Rev. Respir. Dis. 132:999-1004 (1985). [Abstract]
- Issa, F.G., Costas, L.V., Berthon-Jones, M., McCauley, V.J., Bruderer, J. and Sullivan, C.E. Nasal CPAP treatment for obstructive sleep apnea: long-term experience with 117 patients. Am. Rev. Respir. Dis. 131:108 (1985).
- Bye, P.T.B., Ellis, E.R., Donnelly, P.D., Issa, F.G. and Sullivan, C.E. Role of sleep in the development of respiratory failure in neuromuscular disease. Am. Rev. Respir. Dis. 131:108 (1985).
- Issa, F.G. and Sullivan, C.E. The response to total airway occlusion during sleep in patients with obstructive sleep apnea. Proc. Aust. Physiol. Pharmacol. Soc. 15:77 (1985).
- Sullivan, C.E., Issa, F.G., Berthon-Jones, M., McCauley, V.B. and Costas, L.J.V. Home treatment of obstructive sleep apnea with continuous positive airway pressure applied through a nose mask. Bull. Eur. Physiopath. Respir. 20:49-54 (1984).[Abstract]
- Issa, F.G. and Sullivan, C.E. Upper airway closing pressure in obstructive sleep apnea. J. Appl. Physiol. 57:520-527 (1984). [Abstract]
- Issa, F.G. and Sullivan, C.E. Upper airway closing pressure in snorers. J. Appl. Physiol. 57:528-535 (1984). [Abstract]
- Bye, P.T.P., Issa, F.G., Berthon-Jones, M. and Sullivan, C.E. Studies of oxygenation during sleep in patients with interstitial lung disease. Am. Rev. Respir. Dis. 129:27-32 (1984). [Abstract]
- Sullivan, C.E., Issa, F.G., Berthon-Jones, M. and Saunders, N.A. Pathophysiology of sleep apnea. In: Sleep and Breathing. N.A. Saunders and C.E. Sullivan (eds.), Marcel Dekker, Inc. N.Y., pp 299-364 (1984).
- Sullivan, C.E., Berthon-Jones, M. and Issa, F.G. Nocturnal nasal airway pressure for sleep apnea. N. Engl. J. Med. 309:112 (1983).
- Issa, F.G. and Sullivan, C.E. Arousal and breathing responses to airway occlusion in healthy sleeping adults. J. Appl. Physiol. 55:1113-1119 (1983). [Abstract]
- Sullivan, C.E., Berthon-Jones, M. and Issa, F.G. Remission of severe obesity- hypoventilation syndrome after short-term treatment during sleep with nasal continuous positive airway pressure. Am. Rev. Respir. Dis. 128:177-181 (1983). [Abstract]
- Berthon-Jones, M., Issa, F.G., and Sullivan, C.E. Acute upward shift in ventilatory response to CO2 after reversal of obstructive sleep apnea by pneumatic splinting. Aust. NZ. J. Med. 12:224 (1982).
- Sullivan, C.E., Issa, F.G. and Berthon-Jones, M. Reduced severity of obstructive sleep apnea following long-term treatment by continuous positive airway pressure applied through the nose. Aust. NZ J. Med. 12:224 (1982).
- Issa, F.G., Berthon-Jones, M. and Sullivan, C.E. Reversal of heavy and habitual snoring by continuous positive airway pressure applied through the nares. Aust. NZ J. Med. 12:225 (1982).
- Sullivan, C.E., Berthon-Jones, M. and Issa, F.G. Treatment of obstructive sleep apnea with continuous positive airway pressure applied through the nose. Am. Rev. Respir.Dis. 125:107 (1982).
- Lindsay, D.A., Issa, F.G. and Sullivan, C.E. Mechanisms of sleep desaturation in chronic airflow limitation studied with nasal continuous positive airway pressure. Am. Rev. Respir. Dis. 125:112 (1982).
- Issa, F.G. and Sullivan, C.E. Alcohol, snoring and sleep apnea. J. Neurol. Neurosurg. Psychiatry 45:353-359 (1982). [Abstract]
- Sullivan, C.E., Issa, F.G., Berthon-Jones, M. and Eves, L. Reversal of obstructive sleep apnea by continuous positive airway pressure applied through the nares. Lancet i:862-865 (1981). [Abstract]
- Sullivan, C.E. and Issa, F.G. Pathophysiological mechanisms in obstructive sleep apnea. Sleep 3:235-246 (1980).
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