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How to Write a Good Manuscript
Statistical analysis
 

For a proper interpretation of your data, design your study carefully. There are excellent books to help you design your study, determine the number of subjects in your study, selection of these subjects, randomization, etc. Once the data are collected, proper statistical analysis is important for interpretation of the data. There are many web sites on the Internet that provide excellent review of the statistical methods, and some even help you by analyzing such data or offer several examples.

The following web sites provide excellent description of the statistical methods:

  • Statistics: a web site maintained by the Faculty of Medicine, University of Queensland, Australia.
  • SurfStat Australia: offers an extensive glossary, interactive exercises, demonstrating statistical concepts through dynamic graphics. The site is maintained by the Australian National University.
  • STEPS: Statistical Education through Problem Solving is provided by nine departments in seven universities throughout England.
  • HyperStat: An online introductory-level hypertext statistics book.
  • The Mesa Cohort A basic statistics course.
  • Virtual Anesthesia Book: Provides a comprehensive list of statistical resources on the web.

When writing your manuscript, describe the statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results.

  1. Avoid sole reliance on statistical hypothesis testing, such as the use of P values, which fails to convey important quantitative information.
  2. Give details about randomization.
  3. Describe the methods for and success of any blinding of observations.
  4. References for study design and statistical methods should be to standard works (with pages stated) when possible rather than to papers in which the designs or methods were originally reported.
  5. Specify any general-use computer programs used.
  6. Put general description of methods in the Methods.
  7. Avoid nontechnical uses of technical terms in statistics, such as "random" (which implies a randomizing device), "normal," "significant correlations," and "sample." Define statistical terms, abbreviations, and most symbols.
 
     
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